Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2003-01-07
2009-06-30
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
07553623
ABSTRACT:
An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided.
REFERENCES:
patent: 5506105 (1996-04-01), Haydock
patent: 5580970 (1996-12-01), Hendricks et al.
patent: 5639871 (1997-06-01), Bauer et al.
patent: 5654416 (1997-08-01), Cummins et al.
patent: 5750334 (1998-05-01), Cerutti et al.
patent: 6027891 (2000-02-01), Von Knebel-Doberitz et al.
patent: 6027981 (2000-02-01), Wu
patent: 2004/0214302 (2004-10-01), Anthony et al.
patent: 2005/0118568 (2005-06-01), Karlsen
patent: 0 243 221 (1987-10-01), None
patent: 0 373 352 (1990-06-01), None
patent: 0 402 132 (1990-12-01), None
patent: 0 662 518 (1995-07-01), None
patent: 0 774 518 (1997-05-01), None
patent: WO 90/02821 (1990-03-01), None
patent: WO 91/08312 (1991-06-01), None
patent: WO 94/26934 (1994-11-01), None
patent: WO 99/29890 (1999-06-01), None
patent: WO 9929890 (1999-06-01), None
patent: WO 00/00638 (2000-01-01), None
patent: WO 0173135 (2001-10-01), None
patent: WO 01/73135 (2001-11-01), None
patent: WO 02/08460 (2002-01-01), None
patent: WO 03/057914 (2003-07-01), None
patent: WO 03/057927 (2003-07-01), None
Smits et al. (Application of the NASBA nucleic acid amplification method for the detection of human papillomavirus type 16 E6-E7 transcripts J Virol Methods. Jul. 1995;54(1):75-81).
Leone et al. (“Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA” Nucleic Acids Res. May 1, 1998;26(9):2150-5).
Anderson (“Human Papillomavirus and Cervical Cancer” Clin. Microb. Aug. 2002;25(15):113-8).
Smits et al. (“Application of the NASBA nucleic acid amplification method for the detection of human papillomavirus type 16 E6-E7 transcripts” J Virol Methods. Jul. 1995;54(1):75-81.
Smits, H.L., et al. “Application of the NASBA nucleic acid amplification method for the detection of human papillomavirus type 16 E6-E7 transcripts,” Journal of Virological Methods, Amsterdam, NL, vol. 54, No. 1, 1995, pp. 75-81.
Cornelissen, M.T. E. et al., “Uniformity of the splicing pattern of the E6/E7 transcripts in human papillomavirus type 16-transformed human fibroblasts, human cervical premalignant lesions and carcinomas,” Journal of General Virology, Society for General Microbiology, Reading, GB, vol. 71, No. Part 5, (May 1, 1990), pp. 1243-1246.
McNicol, Patricia et al., “Expression of human papillomavirus type 16 E6-E7 open reading frame varies quantitatively in biopsy tissue from different grades of cervical intraepithelial neoplasia,,” Journal of Clinical Microbiology, vol. 33, No. 5, 1995, pp. 1169-1173.
Jeon, Saewha, et al., “Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: Implications for cervical carcinogenesis,” Proceedings of the National Academy of Sciences of the U.S., vol. 92, No. 5, 1995, pp. 1654-1658.
Leone, et al., “Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA,” Nucleic Acids Research, 1998, vol. 26, No. 9, pp. 2150-2155.
Walboomers, Jan M.M., et al., “Human papillomavirus is a necessary cause of invasive cervical cancer worldwide,” Journal of Pathology, J. Pathol. 189: pp. 12-19 (1999).
Bosch, F. Xavier, et al., “Prevalence of Human papillomavirus in cervical cancer: a worldwide perspective,” Journal of the National Cancer Institute, vol. 87, No. 11, Jun. 7, 1995, pp. 796-802.
Kato, Satoshi, et al., “Detection of human papillomaviruses in cervical neoplasias using multiple sets of generic polymerase chain reaction primers,” Gynecologic Oncology, vol. 81, No. 1, (Apr. 2001) pp. 47-52.
Iwasawa, Akihiko, et al., “Human papillomavirus DNA in uterine cervix squamous cell carcinoma and adenocarcinoma detected by polymerase chain reaction,” American Cancer Society, vol. 77, No. 11, (Jun. 1, 1996), pp. 2275-2279.
Doeberitz, M., “New molecular tools for efficient screening of cervical cancer,” vol. 17, 2001, pp. 123-128.
Lanham, S., et al., “HPV detection and measurement of HPV-16, telomerase, and survivin transcripts in colposcopy clinic patients,” J. Clin. Pathol., vol. 54, 2001, pp. 304-308.
Coutlee, F., et al., “Detection of transcripts of human papillomaviruses 16 and 18 in Cancer-derived cell lines and cervical biopsies by enzyme immunoassay for DNA-RNA hybrids following solution hybridization,” J. Clin. Micro, vol. 29, 1991, pp. 968-974.
Database, HPV sequence Database, ′Online! 'Los Alamos National Laboratory; Sep. 1997, Los Alamos National Laboratory; “Human papilloma viruses 1997 compendium,” pp. E6-10-E6-24.
Wu Shuenn-Jue L., et al. “Detection of dengue viral RNA using a nucleic acid sequence-based amplification assay,” Journal of Clinical Microbiology, vol. 39, No. 8, Aug. 2001.
In Re Deuel 34 USPQ 2d 1210 (Fed. Cir. 1995).
Anderson et al., Human papillomavirus and cervical cancer. Clin Microbiol Newslett. Aug. 1, 2002;24(15):113.
Bosch et al., Papillomavirus research update: highlights of the Barcelona HPV 2000 international papillomavirus conference. J Clin Pathol. Mar. 2001;54(3):163-75.
Buck et al. (1999) Design strategies and performance of custom DNA sequencing primers. Biotechniques. vol. 27, pp. 528-536.
Clifford et al., Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer. Jan. 13, 2003;88(1):63-73.
Cuschieri et al., Human papillomavirus type specific DNA and RNA persistence—implications for cervical disease progression and monitoring. J Med Virol. May 2004;73(1):65-70.
Duensing et al., Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer. Mar. 20, 2004;109(2):157-62.
Jeon et al., Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol. May 1995;69(5):2989-97.
Karlsen et al., Use of multiple PCR primer sets for optimal detection of human papillomavirus. J Clin Microbiol. Sep. 1996;34(9):2095-100.
Kievits et al. (1991) NASBA isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection. Journal of Virological Methods. vol. 35, pp. 273-286.
Klaes et al., Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes. Cancer Res. Dec. 15, 1999;59(24):6132-6.
Kraus et al., Human papillomavirus oncogenic expression in the dysplastic portio; an investigation of biopsies from 190 cervical cones. Br J Cancer. Apr. 5, 2004;90(7):1407-13.
Kraus et al., Presence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas. J Clin Microbiol. Apr. 2006;44(4):1310-7.
Lie et al., DNA versus RNA based methods for HPV testing in Norway. Evaluation of Hybrid Capture II and Pre-Tesct HPV-Proofer, a validation study. 21stInternational Papillomavirus Conference, Feb. 20-26, Mexico City, Mexico.
Molden et al., Comparison of human papillomavirus messenger RNA and DNA detection: a cross-sectional study of 4,136 women >30 years of age with a 2-year follow-up of high-grade squamous intraepithelial lesion. Cancer Epidemiol Biomarkers Prev. Feb. 2005;14(2):367-72.
Molden et al., Human papillomavirus E6/E7 mRNA expression in women younger than 30 years of age. Gynecol Oncol. Jan. 2006;100(1):95-100. Epub Sep. 8, 2005.
Munoz et al., Against which human papillomavirus types shall we vaccinate and screen? The international perspective. Int J Cancer. Aug. 20, 2004;11
Babic Christopher M.
Horlick Kenneth R.
Norchip A/S
Wolf Greenfield & Sacks P.C.
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