Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2002-04-09
2009-08-25
Swartz, Rodney P. (Department: 1645)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C536S023700, C536S024300, C536S025320, C435S004000, C435S006120, C435S040500, C435S091200, C435S287200
Reexamination Certificate
active
07579454
ABSTRACT:
The present invention relates to a method for detecting and/or identifying Gram-positive bacteria with high GC content, in particular mycobacteria. The method comprises a nucleic acid amplification reaction and a subsequent hybridization reaction with suitable primers and probes. The invention furthermore relates to oligonucleotides, compositions, solid phases and kits which may be used for carrying out the method of the invention.
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patent: 6583266 (2003-06-01), Smith et al.
patent: 1 390 541 (2005-10-01), None
English translation of International Preliminary Examination Report.
Roller C., et al., “Gram-positive bacteria with a high DNA G+C content are characterized by a common insertion within their 23S rRNA genes,” Journal of General Microbiol 1992; 138: 1167-1175.
Roller C., et al., “In situ probing of Gram-positive bacteria with high DNA G+C content using 23S rRNA-targeted oligonucleotides,” Microbiol 1994; 140: 2849-2858.
Database EMBL ‘Online!’ EBI; May 24, 1996, Cole S.T. et al.: “Mycobacterium tuberculosis H37Rv complete genome; segment 59/162” retrieved from http://www.EBI.AC.UK, Database accession No. Z73902; XP002228144.
Hügle B., et al., “A Closer Look at the Insertion within Helix 54 of the 23S-rRNA of the GenusCorynebacterium(and Related Taxa),” Clin. Lab. 2000; 46: 255-260.
Fu L., et al., “IsMycobacterium tuberculosisa closer relative to Gram-positive or Gram-negative bacterial pathogens?” Tuberculosis 2002; 82(2/3): 85-90.
International Search Report for PCT Application No. PCT/EP02/03956, issued by the European Patent Office on Mar. 6, 2003.
Aniedobe Christopher
Dobe Law Group, LLC
Hain Lifescience GmbH
Swartz Rodney P.
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