Method for detecting esterolytic and proteolytic enzymes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

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435 23, 435 24, 435 29, 435810, C12Q 144, C12Q 136, C12Q 137, C12Q 102

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active

048142719

ABSTRACT:
The present invention relates to new chromogenic amino acid esters and peptide esters of hydroxyisoquinolines and hydroxyquinolines, processes for their preparation and the use of the new esters as substrates for the analytical detection of esterolytic and/or proteolytic enzymes, for example in body fluids, the esters being incorporated into test agents, in particular test strips, in a suitable manner. The new esters are particularly used for the detection of leukocytes, in particular in urine.

REFERENCES:
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patent: 4551428 (1985-11-01), Berger et al.
patent: 4637979 (1987-01-01), Skjold et al.
Jakubke et al, Chemical Abstracts, 65:20211h (1966).
Chladek, Chemical Abstracts, 79:126984g (1972).
Jost et al, Chemical Abstracts, 82:17092y (1975).
Pozdner et al, Chemical Abstracts, 102:79297h (1985).

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