Method for detecting endotoxins

Details Method for detecting endotoxins Method for detecting endotoxins

1976-06-15

1977-07-26

Naff, David M.

Textiles: fiber preparation

23230B, 1951035A, 1951035M, 424 2, G01N 3100, G01N 3316

Patent

active

040381471

ABSTRACT:
A rapid and reliable method is disclosed for determining the presence or absence of endotoxins in solution, including biological liquids such as transudates and exudates. The method comprises a procedure based upon the alteration of a modified coagulation test system by endotoxins produced by gram-negative microorganisms. The method is particularly useful as reliable aid in the early diagnosis and treatment of infections caused by gram-negative microorganisms and to alert the diagnostician to the possibility of septic shock in an infected host.

REFERENCES:
patent: 3179567 (1965-04-01), Owren
patent: 3395210 (1968-07-01), Lenahan et al.
patent: 3486981 (1969-12-01), Speck
patent: 3915805 (1975-10-01), Levin
patent: 3947378 (1976-03-01), Babson
patent: 3960669 (1976-06-01), Innerfield

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