Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1992-08-07
1994-06-28
Rosen, Sam
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
435 79, 435 792, 436 65, 436 86, 436510, 436548, 436 87, G01N 3349, G01N 33493
Patent
active
053246675
ABSTRACT:
The present invention relates to a method for detecting fetal Down syndrome (Trisomy 21), trisomy 13, trisomy 18 and other chromosomal anomalies during prenatal screening by analyzing blood samples from a pregnant woman. More particularly the present invention relates to a method for improving detection efficiency in screening for the anomalies by measuring the amount of the free beta human chorionic gonadotropin (HCG) and nicked or fragmented or aberrant forms of free beta (HCG), all of which are referenced throughout this application as free beta (HCG) in blood samples from pregnant women.
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