Method for detecting cholesterol deposited in bodies of mammals

Details Method for detecting cholesterol deposited in bodies of mammals Method for detecting cholesterol deposited in bodies of mammals

1989-11-27

1991-03-05

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

514 8, 514410, A61K 4900, G01N 3100, G01N 3348, G01N 3710, G01N 3140

Patent

active

049976397

ABSTRACT:
This invention relates to a novel method for detecting cholesterol which is deposited in the bodies of mammals, which method comprises the steps of administering to a host an effective amount of a photosensitizer of at least one member selected from the group consisting of tetrapyrrole carboxylic acids, corresponding di- or tetrahydropyrrole carboxylic acids, mono-, di- or polyamides of said tetrapyrrole carboxylic acids with amino-mono- or dicarboxylic acids, and salts of the above compounds; applying light of sufficient wavelength to the area of said mammal to be examined; and observing the fluorescence emitted from the area in which cholesterol is deposited.

REFERENCES:
patent: 4656186 (1987-04-01), Bommer et al.
patent: 4675338 (1987-06-01), Bommer et al.
patent: 4693885 (1987-09-01), Bommer et al.
Neave, et al. Neurosurgery, vol. 23, pp. 307-12 (1988).

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