Method for detecting Cheyne-Stokes respiration in patients...

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

Reexamination Certificate

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C600S323000

Reexamination Certificate

active

06839581

ABSTRACT:
The present invention provides a diagnostic tool for detection of Cheyne-Stokes Respiration (CSR). This invention also provides a method for development of the diagnostic tool. The method comprises the steps of performing overnight oximetry recordings in patients suspected of sleep disordered breathing. Spectral analysis is performed on the oximetry recordings to obtain a set of parameters which can be used in the construction of a classification tree and a trained neural network. The diagnostic tools of the present invention can be used for classification of a patient as having CSR or obstructive sleep apnea.

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Blackshear et al.,Nocturnal Dyspnea and Atrial Fibrillation Predict Cheyne-Stokes Respirations in Patients with Congestive Hearth Failure, Arch Intern Med, Jun. 26, 1995, vol. 155(12), pp. 1297-1302.
Dowdell et al.,Cheyne-Stokes Respiration Presenting as Sleep Apnea Syndrome. Clinical and Polysomnographic Features. Am Rev Respir Dis, Apr. 1990, vol. 141(4 Pt. 1), pp. 871-879.
Hanley et al.Pathogenesis of Cheyne-Stokes Respiration in Patients with Congestive Heart Failure. RElationship to Arterial PCO2. Chest, 1993, vol. 104, pp. 1049-1084.
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