Method for detecting carcinomatous and precarcinomatous colo-rec

Details Method for detecting carcinomatous and precarcinomatous colo-rec Method for detecting carcinomatous and precarcinomatous colo-rec

1987-10-23

1990-03-27

Naff, David M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

424 11, 424 9, 436 3, 436548, 436800, 436804, 436813, 530387, 935110, G01N 3353, G01N 33577, A61K 3900, C12N 100

Patent

active

049120310

ABSTRACT:
A method for distinguishing between carcinomatous and/or precarcinomatous colo-rectal disease and histologically similar conditions due to diseases that are not carcinomatous or precarcinomatous comprising contacting colo-rectal tissue with an antibody that binds to blood group substance H and determining the presence of carcinomatous or precarcinomatous disease upon a finding of bound antibody, or the absence of such disease upon the finding of no bound antibody.

REFERENCES:
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patent: 4678747 (1987-07-01), Lloyd et al.
patent: 4814275 (1989-03-01), Durda et al.
Cooper et al., Am. J. Clin Pathol., vol. 69, 1978, p. 594-598.
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Erik et al., Archives of Biochemistry and Biophysics, vol. 187, No. 2, Apr. 30, 1978, p. 366-375.
Holmgren et al., British Medical Journal, vol. 288, May 1984, p. 1479-1482.
Kim et al., Cancer Research, vol. 35, Aug. 1975, p. 2092-2097.

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