Method for detecting cancerous tissue using optical spectroscopy

Details Method for detecting cancerous tissue using optical spectroscopy Method for detecting cancerous tissue using optical spectroscopy

1996-03-18

1998-06-23

Smith, Ruth S.

Surgery

Truss

Pad

356301, 356318, A61B 600

Patent

active

057690812

ABSTRACT:
A method for detecting cancerous tissue using optical spectroscopy and Fourier analysis. According to a preferred embodiment, a tissue sample is illuminated with light at a wavelength of approximately 300 nm. Next, a fluorescence emission spectrum for the tissue sample is obtained by measuring the resultant fluorescence from the tissue sample over the spectral region from approximately 320 nm to approximately 580 nm. The phase and amplitude for the first three Fourier transform harmonics are then determined. The phase and amplitude determinations for one or more of the three harmonics are then compared to appropriate standards obtained from cancerous and non-cancerous tissue samples. The accuracy of the method can be improved further by comparing the phase and amplitude calculations for at least two harmonics.

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