Method for detecting cancer cells and monitoring cancer therapy

Details Method for detecting cancer cells and monitoring cancer therapy Method for detecting cancer cells and monitoring cancer therapy

2011-03-22

2011-03-22

Bertoglio, Valarie (Department: 1632)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C424S093600, C435S006120

Reexamination Certificate

active

07910093

ABSTRACT:
Disclosed herein are methods for identifying cancer cells and monitoring anti-cancer therapy in the body of a mammal by systemically delivering Sindbis viral vectors. The vector can specifically target and identify tumor cells in mice growing subcutaneously, intraperitoneally, intrapancreatically, or in the lungs. These findings demonstrate the remarkable specificity of the Sindbis vector system that is relatively safe and can specifically target tumor cells throughout the body via the bloodstream.

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