Method for detecting biological activities in a specimen

Details Method for detecting biological activities in a specimen Method for detecting biological activities in a specimen

1993-08-19

1994-12-13

Russel, Jeffrey E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 435 29, 435291, 435294, 435817, 435968, 436172, 436800, 436805, 382 6, C12Q 104, C12M 134, G01N 2176

Patent

active

053729366

ABSTRACT:
A method, a sensor and apparatus for detecting biological activities in a specimen, for example in a blood sample, are provided in which a sealable container is sealed with a culture medium therein into which the sample is introduced, metabolic processes are enhanced in the presence of microorganisms in the sample and changes taking place in the concentrations of the substances. Such processes are detected and monitored with an excitation and detection assembly assigned to concentration sensors, in the form of optodes which are optically coupled to the excitation and detection assembly and to thereby to an evaluation unit for determining concentration changes of the substances over time as indications of the presence of microorganisms.

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Japanese Patent 57207861, Patent Abstracts of Japan, vol. 7 No. 64 (P-183) (1209) Mar. 17, 1983.
"Biochemical Tests for Identification of Medical Bacteria", MacFaddin, The Williams & Wilkins Company, 1976 pp. 108-118 and pp. 187-194.

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