Method for detecting base mutation

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S023100, C536S024300

Reexamination Certificate

active

10688272

ABSTRACT:
The present invention relates to methods for precisely and effectively detecting mutations of organism.

REFERENCES:
patent: WO 01/90419 (2001-11-01), None
Kim, Mar. 2003, Korean J. Genetics, vol. 25, pp. 63-75.
New England Biolabs Catalog, 2000, pp. 192, 202, and 203.
Niesters, Aug. 2002, J. Med. Microbiol., vol. 51, pp. 695-699.
Nguyen, Jan. 1998, J. Med. Virology, vol. 54, pp. 20-25.
Hwang et al., “Detection Of Hepatitis B Virus Variants Associated With Lamivudine Resistance Using RFMP,” The Korean Journal of Hepatology, 2003, vol. 9, Supp. 3 (w/ English translation).
Kim et al., “New Hepatitis C Virus Genotyping Assay As A Routine Method By Novel RFMP,” The Korean Journal of Hepatology, 2003, vol. 9, Supp. 3 (w/ English translation).
Kim et al., “The Study Of Development Of Lamivudine Resistant Mutants And Viral Breakthrough,” The Korean Journal of Hepatology, 2003, vol. 9, Supp. 3 (w/ English translation).
Kim et. al., “Novel Mass Spectrometric Assay for Monitoring Drug Resistance in Hepatitis B Virus during Lamivudine Therapy,” Korean J. Genetics, 2003, 25(1):63-75.
Orita et al., Rapid and Sensitive Detection of Point Mutations and DNA Polymorphisms Using the Polymerase Chain Reaction, Genomics, 1989, 5:874-9.
Tobe et al., “Single-well genotyping of diallelic sequence variations by a two-color ELISA-based oligonucleotide ligation essay,” Nucleic Acids Research, 1996, 24(19): 3728-32.
Pastinen et al., “Minisequencing: A Specific Tool for DNA Analysis and Diagnostics on Oligonucleotide Arrays,” Genome Research, 1997, 606-14.

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