Method for detecting antibodies to thrombomodulin in patients

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 721, 435 793, 435 794, 435 795, 435 13, 435961, 435962, 435967, 435968, 436531, 436 69, 536 271, 536 281, 536 291, 530386, 5303879, 5303891, 5303893, G01N 3353

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active

056396252

ABSTRACT:
A novel method of detecting antibodies to thrombomodulin in plasma or serum as an indication of an individual's propensity to thrombosis or inflammation is disclosed. A method for identifiying patients at risks of thrombosis or glomerular nephritis by monitoring autoantibodies to truncated soluble thrombomodulin is revealed. A preferred method is an ELISA assay to detect antibodies to thrombomodulin.

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