Method for detecting and monitoring cancer

Details Method for detecting and monitoring cancer Method for detecting and monitoring cancer

1983-04-25

1985-01-15

Turk, Arnold

Chemistry: analytical and immunological testing

Cancer

436 87, 436175, 436177, G01N 3102, G01N 3348, G01N 3368

Patent

active

044938985

ABSTRACT:
A method for diagnosing and monitoring cancer, which comprises precipitating certain components from blood serum by addition of a benzenesulfonic acid or a benzylsulfonic acid, determining the sialic acid content of the supernatant, and comparing its sialic acid content with the sialic acid content of sera from healthy subjects after identical treatment. The determination of the sialic acid by the thiobarbituric acid colorimetric method is improved by addition of N,N-dimethylacetamide during development of the chromophore.

REFERENCES:
patent: 4115062 (1978-09-01), Morre et al.
patent: 4146603 (1979-03-01), Davidson et al.
patent: 4171204 (1979-10-01), Schwenzer et al.
patent: 4180556 (1979-12-01), Kim et al.
Warren, J. of Biological Chemistry, vol. 234, No. 8, pp. 1971-1975, (Aug. 1959).

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