Method for detecting a risk of hypertension and uses thereof

Details Method for detecting a risk of hypertension and uses thereof Method for detecting a risk of hypertension and uses thereof

2006-04-18

2006-04-18

Jones, W. Gary (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C536S023500, C536S024310, C536S024330

Reexamination Certificate

active

07029849

ABSTRACT:
This invention relates to a method for detecting a risk of hypertension and for targeting antihypertensive treatment in a subject, the method comprising isolating genomic DNA from said subject, determining the DNA sequence comprising a nucleotide sequence encoding a variant α2B-adrenoceptor protein.

REFERENCES:
patent: 5595880 (1997-01-01), Weinshank et al.
patent: WO 99/52942 (1999-10-01), None
patent: WO 01/29082 (2001-04-01), None
Small et al.(Journal of Biological Chemistry, vol. 267, No. 7, Feb., 16 2001).
Heinonen et al, J. Clin. Endocrinol. vol. 84, No. 7 1999.
Baldwin et al. Am J. Hypertens. 12:853-857,1999 (Abstract).
Munroe, P.B. et al. Curr.Opin. Genet. Dev. 10::325-329: 2000.
Von Wowern et al.(Hypertension. 2004; 43: 592).
Hacker et al.(Gut, 1997, vol. 40, pp. 623-627).
Pennisi, Science, 281 (5384):1787-1789.
Baldwin et al.(American Journal of Hypertension, 1999; 12:853-857).
Heinonen et al.(The Journal of Clinical Endocrinology and Metabolism vol. 84, No. 7 1999, 2429-2433).
Baldwin et al., “Identification of a Polymorphic Glutamic . . . ”,American Journal of Hypertension,vol. 12, 1999, pp. 853-857.
Small et al., “Polymorphic Deletion of Three Intracellular . . . ”,The Journal of Biological Chemistry,vol. 276, No. 7, 2001, pp. 4917-4922.
Snapir et al., “An Insertion/Deletion Polymorphism . . . ”,Journal of the American College of Cardiology,vol. 37, No. 6, 2001, pp. 1516-1522.
Jewell-Motz et al., “An Acidic Motif within the Third Intracellular . . . ”,Biochemistry,vol. 34, 1995, pp. 11946-11953.
Heinonen, et al., “Identification of a Three-Amino Acid Deletion . . . ”,The Journal of Clinical Endocrinology and Metabolism,vol. 84, No. 7, 1999, pp. 2429-2433.

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