Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1986-03-04
1989-06-20
Marantz, Sidney
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4351723, 43524027, 436 63, 436174, 436519, 436520, 436529, 436533, 436534, 436548, 436804, 436811, 530350, 530387, 935110, G01N 3353, G01N 33543, G01N 33555, G01N 33577
Patent
active
048408948
ABSTRACT:
A method for detecting the presence in a human of an integral membrane calcium-binding protein associated with essential hypertension which comprises isolating tissue from a human, treating the tissue to obtain integral membrane proteins, contacting the proteins thus obtained with a first antibody molecule which binds to the integral membrane calcium binding protein to form an detectable protein-antibody complex, and detecting the complex so formed.
Further, methods for quantitatively determining the amount of an integral membrane calcium-binding protein and the messenger RNA encoding said protein, diagnostic methods for identifying individuals predisposed to essential hypertension, and protein and messenger RNA associated with said hypertension.
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Abbott Richard E.
Cowen Lisa A.
Kowarski Szloma
Schachter David
Marantz Sidney
The Trustees of Columbia University in the City of New York
White John P.
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