Method for derivitizing electrodes and assay methods using such

Details Method for derivitizing electrodes and assay methods using such Method for derivitizing electrodes and assay methods using such

1997-09-03

2000-10-17

Huff, Sheela

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 5, 435 6, 435 71, 435 77, 435817, 436526, 436518, 204400, 204403, C12Q 100

Patent

active

06132955&

ABSTRACT:
An electrode can be derivitized by contacting it with a derivitizing solution to make it more sensitive to a desired analyte signal as opposed to interfering signals in an assay. Particularly, in an electrochemiluminescence (ECL) immunoassay the working electrode can be derivitized to be more sensitive to desired analyte signals, as opposed to interfering non-bound conjugate or serum matrix signals.

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Blackburn et al. "Electrochemiluminescence Detection for Development of Immunoassays and DNA Probe Assays for Clinical Diagnostics," 37, Clinical CHemistry 1534-1539 (1991).

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