Method for delivering melanin to hair follicles

Details Method for delivering melanin to hair follicles Method for delivering melanin to hair follicles

1994-01-13

1997-06-24

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 701, 424 702, 424 706, 514 2, A61K 9127, A61K 706

Patent

active

056415087

ABSTRACT:
The present invention describes a method for targeted and specific delivery of beneficial compounds, including dyes, proteins, and nucleic acids for gene therapy, to hair follicle cells using liposomes encapsulating the beneficial compound. Particularly preferred methods describe delivery of tyrosinase to the hair follicle for the purpose of improving hair color or condition, either by encapsulating the compound in liposomes, or by encapsulating a nucleic acid capable of expressing the protein in liposomes.

REFERENCES:
patent: 3993436 (1976-11-01), Fujinuma
patent: 5006331 (1991-04-01), Gaskin
Smitz et al. Cancer Research 52(23) 1992 pp. 6638-6645.

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