Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Patent
1994-08-12
1997-02-18
Feisee, Lila
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
4241431, 4241501, 5303911, 5303913, 5303873, 5303917, 435188, 435 7021, C07K 1624, A61K 39395
Patent
active
056039310
ABSTRACT:
Hybrid reagents comprising a first portion having an affinity for a cellular target and a second portion having an affinity for a bioactive molecule are described, said hybrid reagents being capable of selectively releasing the bioactive molecule in response to a change in pH. The hybrid reagents of the present invention can be used diagnostically or therapeutically.
REFERENCES:
Waldmann Science vol. 252:1657, 1991.
Harris et al. TibTeh vol. 11, 1993, p. 42.
Hird et al. Genes and Caneer Carney et al. ed. p. 183 1990.
Boston Biomedical Research Institute
Feisee Lila
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