Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Reexamination Certificate
2004-10-05
2009-11-10
Channavajjala, Lakshmi S (Department: 1611)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
C424S069000, C424S070100, C514S357000, C514S442000, C514S616000
Reexamination Certificate
active
07615230
ABSTRACT:
The present invention is directed to the topical application of the malonamide ACAT inhibitors described by Formula I. Other aspects of the invention are directed to topical formulations of these diamides, their use to treat sebaceous gland disorders and their use to alleviate oily skin.
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patent: 433662 (1991-06-01), None
patent: WO 01/56556 (2001-08-01), None
Yagyu et al., Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia, Journal of Biological Chemistry, pp. 21324-21330, vol. 275/28, Apr. 20, 2000.
Burkhardt, J., et al., “Effect of Topical Treatment with CP-118,313 in Dogs on the Morphology of Sebaceous Glands—Study of the Dose Response Relationship”, Study #DI-99-109, 115, 123.
Kostlan Catherine R.
Raheja Raj Neil
Tugnait Meera
Wade Kimberly
Channavajjala Lakshmi S
Graceway Pharmaceuticals, LLC
McDermott Will & Emery LLP
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