Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Albumin
Patent
1994-12-19
1998-01-20
Degen, Nancy
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Albumin
530402, 530408, 530416, 530427, 514 12, C07K 136, C07K 14765, C07K 116, A61K 3838
Patent
active
057102538
ABSTRACT:
A method for decoloring a recombinant human serum albumin by treating the albumin with a reducing agent is disclosed. Also, a method for decoloring a recombinant human serum albumin by treating the albumin with a method removing free polysaccharides with a cation exchanger followed by heat treatment is disclosed. The present invention provides a recombinant human serum albumin, coloring of which is fully suppressed by preventing binding of certain coloring components, which are contained in the raw materials or contaminants secreted by a microorganism, to human serum albumin so as not to cause coloring of the human serum albumin.
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Furuhata Naoto
Noda Munehiro
Ohmura Takao
Ohtani Wataru
Sumi Akinori
Degen Nancy
The Green Cross Corporation
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