Method for culturing hematopoietic cells

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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4352401, 4352402, 435240241, 43524025, C12N 502, C12N 506, C12N 508

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054609640

ABSTRACT:
A method for culturing mammalian hematopoietic, preferably stem cells, is provided comprising maintaining a population of human hematopoietic cells in a non-contacting relationship to a population of cultured stromal cells, which populations are in preferably liquid stromal growth medium connection, so that the ability of the stem cells in said population to differentiate and self-replicate is maintained during an extended culture period.

REFERENCES:
patent: 4342828 (1982-08-01), Takaku et al.
patent: 4714680 (1987-12-01), Civin
patent: 4721096 (1988-01-01), Naughton et al.
patent: 4808611 (1989-02-01), Cosman
patent: 4873191 (1989-10-01), Wagner et al.
patent: 4902783 (1990-02-01), Goda et al.
patent: 4946437 (1990-08-01), Sredni et al.
patent: 4965204 (1990-10-01), Civin
patent: 5004681 (1991-04-01), Boyse et al.
patent: 5035994 (1991-07-01), Civin
patent: 5061620 (1991-10-01), Tsukamoto et al.
patent: 5104804 (1992-04-01), Humphries et al.
patent: 5139951 (1992-08-01), Butz et al.
patent: 5192553 (1993-03-01), Boyse et al.
Greenberger in Hematopoiesis (ed. D. W. Golde) pp. 203-242 Churchill Livingstone N.Y. 1984.
Knapp et al. Leukocyte Typing IV, CD Guide, p. 1083 CD 34 (1992).
Wang et al. Ann NY Acad Sci 665: 274-284 (1992).
Koller et al. J Cell Biochem Suppl 16: 135 (1992).
Broxmeyer et al. Blood 76: 1110-1116 (1990).
Gluck et al. Exp Hematol 17: 398-404 (1989).
Caldwell J. Cell Physiol. 147: 344-353 (1991).
Testa ACTA Haematol 86: 122-127 (1991).
Dorshkind Ann Rev Immunol. 8:111-137 (1990).
Hurley et al. Blood 82: 21A, 1993.
Gupta et al. Blood 82: 21A, 1993.
Verfaillie et al. J Exp Med 179: 643-649 (1994).
Verfaillie Blood 82: 2045-2053 (1993).
Verfaillie Blood 79: 2821-2826 (1992).
L. Simonovitch, J. Cell. Comp. Physiol., 64 23 (1964).
T. M. Dexter et al., J. Cell Physiol., 91, 335 (1977).
R. Shields et al., J. Cell. Physiol., 91 345 (1977).
T. M. Dexter et al., J. Exp. Med., 145, 1612 (1977).
S. Gartner et al., PNAS USA, 77, 4756 (1980).
I. R. G. Toogood et al., Leukemia Res., 4, 449 (1980).
S. A. Bentley, Exp. Hematol., 9, 308 (1981).
F. T. Slovick et al., Exp. Hematol., 12, 327 (1984).
M. Y. Gordon et al., Internat. J. Cell Cloning, 1, 429 (1983).
W. W. Kwok et al., PNAS USA, 83, 4552 (1986).
I. R. Freshney, "Hemopoeitic Cells," in Culture of Animal Cells, A. R. Liss, N.Y. (187) at pp. 284-288.
M. Y. Gordon et al., J. Cell. Physiol., 130, 150 (1987).
M. Y. Gordon et al., Nature, 326, 403 (1987).
T. Friedmann, Lancet, 1271 (Jun. 4, 1988).
G. J. Spangrude et al., Science, 241, 58 (1988).
J. Brandt et al., J. Clin. Invest., 82, 1017 (1988).
T. Friedmann, Science, 244, 1275 (1989).
I. Bertoncello et al., Exp. Hematol., 17, 171 (1989).
S. J. Szilvassy, PNAS USA, 86, 8798 (1989).
H. J. Sutherland et al., Blood, 74, 1563 (1989).
C. Verfaillie et al., J. Exp. Med., 172, 509 (1990).
M. A. S. Moore, Cancer Surveys, 9, 7 (1990).
D. M. Bodine, Ann. N.Y. Acad. Sci., 612, 415 (1990).
D. Zipori et al., Exp. Hematol., 8, 816 (1990).
P. M. Lansdorp et al., J. Exp. Med., 172, 363 (1990).
R. G. Andrews et al., J. Exp. Med., 172, 355 (1990).
H. H. Gerhartz et al., Blood, 76, 274a, Abstract 1087 (1990).
H. J. Sutherland et al., PNAS USA, 87, 2584 (1990).
J. Brandt et al., J. Clin. Invest., 86, 932 (Sep. 1990).
B. D. Luskey et al., Annal. N.Y. Acad. Sci., 612 398 (1990).
L. W. M. M. Terstappen et al., Blood, 77, 1218 (Mar. 1991).
R. M. Lemoli et al., Blood, 77, 1829 (Apr. 15, 1991).
E. Bruno et al., Blood, 77, 2339 (Jun. 1, 1991).
J.-H. Shieh et al., J. Immunol., 147, 2984 (1991).
C. M. Verfaillie et al., Blood, 77, 263 (1991).
H. J. Sutherland et al., Blood, 78, 666 (1991).
C. Smith et al., Blood, 77, 2122 (May 15, 1991).
M. A. S. Moore, Blood, 78, 1 (Jul. 1, 1991).
M. A. S. Moore, Cancer Supp., 2718 (May 15, 1991).
R. M. Schwartz, PNAS USA, 88, 6760 (Aug., 1991).
E. F. Srour et al., Blood Cells, 17, 287 (1991).
C. C. Fraser et al., PNAS USA, 89, 1968 (Mar. 1992).
C. M. Baum et al., PNAS USA, 89, 2804 (Apr. 1992).
Costar "Transwell" Tech Data Sheet (no date).
Transplantation, vol. 48, issued Oct. 1989, A. H. Frankel et al., "Requirements for the Induction of Allospecific CD8+Suppressor T Cells in the Rat Primary Mixed Lyumphocyte Response", pp. 639-646.

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