Method for creating specific, high affinity nuclear receptor...

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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C702S020000, C703S011000, C707S793000, C435S007100

Reexamination Certificate

active

10317034

ABSTRACT:
This invention pertains to agonists that activate nuclear receptors. These agonists include an extension that contacts a region of the nuclear receptor outside the native ligand binding pocket. Methods for producing, identifying and designing such agonists are included along with nuclear receptor agonist complexes and libraries of agonists.

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