Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic
Patent
1994-10-27
1996-12-17
Eisenschenk, Frank C.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is organic
436531, 436518, 5303911, 521 65, G01N 33547, G01N 33545, C08J 928, C07K 1714
Patent
active
055852785
ABSTRACT:
Antibody-latex reagents are prepared that utilize a novel site-specific covalent linkage of antibodies, via their interfering Fc moieties, onto novel polymeric latex sphere substrates, thereby preserving the antigen binding sites of the antibodies. This immobilization of antibodies is essential for high specific activity and sensitivity assays, and is also economical and much simpler than other covalent immobilizations.
REFERENCES:
patent: 4164558 (1979-08-01), von Schulthess et al.
patent: 4184849 (1980-01-01), Cambiaso et al.
patent: 4210723 (1980-07-01), Dorman et al.
patent: 4397960 (1983-08-01), Moussebois et al.
patent: 4401765 (1983-08-01), Craig et al.
patent: 4480042 (1984-10-01), Craig et al.
patent: 5095097 (1992-03-01), Hermentin et al.
Medcalf et al., Clin. Chem., 36(3):446, 1990.
Tan et al., PNAS, 1990, 87(1):162.
Thakkar et al., Clin. Chem. 1981, 27(7):1205.
Fernandez Jose I.
Leong Koon-Wah
Raimondo Oscar
Vunnam Ranga R.
Bayer Corporation
Eisenschenk Frank C.
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