Method for correcting a spectral image for optical...

Details Method for correcting a spectral image for optical... Method for correcting a spectral image for optical...

2011-05-17

2011-05-17

Evans, F. L (Department: 2877)

Optics: measuring and testing

By dispersed light spectroscopy

With raman type light scattering

C356S318000

Reexamination Certificate

active

07944556

ABSTRACT:
A spectral image is corrected for optical aberrations. Tissue is exposed to a high-intensity, narrow band of light. The narrow band of light is scattered by at least one analyte in the tissue. Raman signals are optically collected from the scattered light. The Raman signals are directed to a wavelength-separating device. The Raman signals are detected as a function of intensity and wavelength to create the spectral image. The spectral image is corrected for optical aberrations using a software algorithm to spatially reassign intensity. The software may be adapted to use a reference image to make dynamic corrections. Fluorescence signals may also be collected.

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