Method for conversion of .beta.-aspartylphenylalanine derivative

Details Method for conversion of .beta.-aspartylphenylalanine derivative Method for conversion of .beta.-aspartylphenylalanine derivative

1986-05-01

1987-06-16

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

560 24, 562442, C07D 2408

Patent

active

046737448

ABSTRACT:
A method for converting .beta.-aspartylphenylalanine derivative (1) to .alpha.-aspartylphenylalanine derivatives (2) and (3), said derivatives having the following structures: ##STR1## which comprises: reacting said .beta.-aspartylphenylalanine derivative (1) at a temperature of from 0.degree. to 200.degree. C. for a time period of from 30 minutes to 80 hours, in a C.sub.1 to C.sub.4 alcohol solvent with or without stirring, wherein R and R' represent hydrogen or an alkyl group having from 1 to 4 carbon atoms.

REFERENCES:
patent: 3560503 (1971-02-01), Anand et al.
patent: 4088649 (1978-05-01), Smith et al.

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