Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or...
Reexamination Certificate
2000-03-23
2004-08-17
Brumback, Brenda (Department: 1654)
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
C435S173700, C435S173900, C501S001000, C423S299000, C423S308000
Reexamination Certificate
active
06777214
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a ceramic (including powder and fiber) treated by polarization and, more particularly, to a method for growing, decreasing, activating or inactivating cells, bacteria or the like and a material therefor, in which a ceramic treated by polarization is utilized.
The present invention also relates to a method for selective adsorption of proteins by utilizing difference in the absorption properties among surfaces of a ceramic which are formed by treating the ceramic by polarization and a material therefor.
The present invention further relates to a cement material for filling bones and dental applications which comprises powder of a ceramic treated by polarization.
2. Description of Related Art
It has been proposed by the present inventors in Japanese Patent Application Laid-Open No. Heisei 10(1998)-324584 that a ceramic, an inorganic material, having affinity to biomaterials which is obtained by treating a ceramic by polarization can be used as a tooth material to reinforce or replace a tooth bone and increases the growth rate of crystals similar to bone materials.
SUMMARY OF THE INVENTION
An object of the present invention is to provide a method for controlling organisms, i.e., growing, decreasing, activating and inactivating cells and tissues of organisms, which can be applied to a wide range of areas such as the medical, dental and biochemical areas and to antibiotic applications and a material therefor, a method for selective adsorption of proteins and a material therefor and a cement material for filling bones and dental applications.
The present invention provides:
(1) A method for controlling organisms which comprises growing, decreasing, activating or inactivating cells, bacteria, viruses or fungi at an N-surface or a P-surface of a ceramic which is formed by treating the ceramic by polarization;
(2) A material for controlling organisms which is a ceramic treated by polarization so that cells, bacteria, viruses or fungi are grown, decreased, activated or inactivated at an N-surface or a P-surfaces of the ceramic which is formed by the treatment;
(3) A method for selective adsorption of proteins which comprises selectively adsorbing drugs, nutrients and proteins by utilizing difference in adsorption properties among an N-surface, an O-surface and a P-surface of a ceramic which are formed by treating the ceramic by polarization;
(4) A material for selective adsorption of proteins which is a ceramic treated by polarization so that drugs, nutrients and proteins are selectively adsorbed due to difference in adsorption properties among an N-surface, an O-surface and a P-surface of a ceramic which are formed by treating the ceramic;
(5) A cement material for filling bones and dental applications which comprises powder or fiber of a ceramic treated by polarization;
(6) A biomaterial which is obtained by treating a ceramic having affinity to biomaterials by polarization in an atmosphere of steam at a temperature from a room temperature to 1,000° C.; and
(7) A biomaterial which is obtained by treating a ceramic having affinity to biomaterials by polarization at a voltage from 10 to 100,000 V/cm.
REFERENCES:
patent: 2976246 (1961-03-01), Egerton et al.
patent: 62-72373 (1987-04-01), None
patent: 7-284527 (1995-10-01), None
patent: 9-329602 (1997-12-01), None
patent: 10-324584 (1998-12-01), None
File Medline On Stn. Abstract No. (AN NO.)92212356. Moriya et al. ‘Experimental Study on the Application of Direct Current to the Intra-Osseous Implant’, Nippon Hotetsu Shika Gakkai Zasshi vol. 34, No. 2, (Apr. 1990), pp. 309-317. Abstract Only.*
Kobayashi et al. ‘Vectorial Effects on Tissue Reaction of Electrically Poled Hydroxyapatite Ceramic’, Bioceramics, Proceedings of the 12thInternational Symposium on Ceramics in Medicine, vol. 12, pp. 291-294. Oct. 1999.*
Jianqing, F. et al., “Promotion Of Osteogenesis By A Piezoelectric Biological Ceramic,”Biomaterials, Elsevier Science Publishers B.V., Barking, GB, vol. 18, No. 23, Dec. 1, 1997, pp. 1531-1534.
Park, J.B. et al., “Piezoelectric Ceramic Implants: In Vivo Results”,J. Biomed. Mater. Res., vol. 15, No. 1, Jan. 1981, pp. 103-110.
Feng, J. et al., “An Investigation On The Ceramic Composite Of Th e Biological Piezoelectric Implants”, Feng; H.,Polymers and Biomaterials, Elsevier Science Publishers, B.V., Amsterdam, 1991, pp. 367-371.
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Brumback Brenda
Gupta Anish
Price Heneveld Cooper DeWitt & Litton LLP
Yuugen Gaisha Neichamateriaru
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