Method for controlled release of compounds having antimicrobial

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435128, 435136, 435197, 435212, 424 7809, C12P 702, C12P 1300, C12P 740, C12N 918, A61K 3174

Patent

active

061501468

ABSTRACT:
A novel method for controlled release of compounds having antimicrobial activity and a novel coating composition capable of controlled release of compounds having antimicrobial activity is provided.
This invention relates to a method for releasing a compound having antimicrobial activity from a matrix at a controlled rate, which comprises incorporating an enzyme and a substrate in said matrix beforehand to allow said enzyme and said substrate to react with each other in said matrix to thereby produce said compound having antimicrobial activity; and further relates to a coating composition comprising a film-forming resin, an enzyme, and a substrate, said enzyme being capable of reacting with said substrate to produce a compound having antimicrobial activity.

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Kennedy et al. J. Chem. Soc. Perkin Trans. 1 (1978) 9: 1058-66 (abstract only).

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