Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1988-05-25
1992-10-06
Elmore, Carolyn
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
C12P 764
Patent
active
051531267
ABSTRACT:
A method for continuous preparation of highly pure monoglyceride comprises the steps of esterifying fatty acid dissolved in a nonpolar solvent at the interface between the nonpolar solvent phase and a polar solvent phase containing glycerol, water and dispersed lipase, the polar phase being located below the nonpolar phase, continuously taking out the nonpolar solvent phase, cooling the taken out phase to isolate the resulting monoglyceride by precipitation, and bringing back the remaining solution to the esterification system.
By this method, monoglycerides having high purity can be produced continuously and at low cost, and further monoglycerides of straight-chained fatty acids can preferentially obtained even though the fatty acids used contain branched fatty acids.
REFERENCES:
patent: 4275011 (1981-06-01), Tanaka et al.
Glyceride Synthesis by Four Kinds of Microbial Lipase, Yoshio Tsujisaka, Susumu Okumura and Mieko Iwai, Biochimica et Biophysica Acta, 489 (1977) 415-422.
Some Characteristics of Continuous Glyceride Synthesis by Lipase in a Microporous Hydrophobic Membrane Bioreactor, Mohammad Mozammel Hoq, Haruko Tagami, Tsuneo Yamane and Shoichi Shimizu, Agric. Biol. Chem., 49(2), 335-342, 1985.
Enzymatic Fat Hydrolysis and Synthesis, Warner M. Linfield, Robert A. Barauskas, Lorraine Sivieri, Samuel Serota and Robert W. Stevenson, Sr., JAOCS, vol. 61, No. 2 (Feb. 1984).
Oba Kenkichi
Schroder Roland
Elmore Carolyn
Lion Corporation
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