Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1987-05-12
1990-07-03
Warden, Robert J.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
43524046, 43524047, 435243, 435255, 435256, 435286, 435312, 435813, C12N 502
Patent
active
049390872
ABSTRACT:
Bioprocessing apparatus and method using centrifugal acceleration of cells to maintain a culture within a reaction zone. The reactor has an inflow at a relatively distance inlet and an outflow at an inwardly spaced point toward the rotational axis. The reaction chamber has an inwardly diverging zone with a velocity gradient which captures cells of varying sizes. A recycle system is preferably used to recycle medium containing nutrients for the culture microbes. Byproducts of the cells are removed by the circulated medium and can be extracted using a desired extraction process.
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Brouns Thomas M.
Elliott Michael L.
Van Wie Bernard J.
McMahon Timothy M.
Warden Robert J.
Washington State University Research Foundation, Inc.
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