Method for construction of oligonucleotide microarrays

Combinatorial chemistry technology: method – library – apparatus – Method of creating a library

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C435S006120

Reexamination Certificate

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07829505

ABSTRACT:
Disclosed herein is a method for the preparation of oligonucleotide microarrays obviating the drawbacks to an extent, such as time consuming complex chemical reactions, preparation of modified supports/oligomer modifying reagents, use of activating/condensing reagent, low signal to noise ratio, poor immobilization and hybridization efficiencies, etc. Further, the prepared arrays can be used to detect single or multiple nucleotide mismatches using hybridization assay.

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