Method for constructing reconstructed skin

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of co-culturing cells

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C623S015120, C424S423000

Reexamination Certificate

active

07736894

ABSTRACT:
The present invention relates to a method for constructing human skin tissue, in which human skin tissue is reconstructed on a body surface of an immunodeficient non-human animal.

REFERENCES:
patent: 5702945 (1997-12-01), Nagels et al.
patent: 6040493 (2000-03-01), Cooke et al.
patent: 1-122723 (1989-08-01), None
patent: 3-116830 (1991-12-01), None
patent: 2002-505859 (2002-02-01), None
patent: 99/45770 (1999-09-01), None
Bell et al, “Living Tissue Formed in vitro and Accepted as Skin-Equivalent Tissue of Full Thickness”, Science, 1981, vol. 211, No. 4486, pp. 1052-1054.
Bell et al, “The Reconstitution of Living Skin” Journal of Investigative Dermatology, 1983, vol. 81 Suppl. pp. 2s-10s.
Boyce et al, “Pigmentation and Inhibition of Wound Contraction by Cultured Skin Substitutes with Adult Melanocytes After Transplantation to Athymic Mice” Journal of Investigative Dermatology, 1993, vol. 100, pp. 360-365.
Prunieras et al, “Methods for Cultivation of Keratinocytes with an Air-Liquid Interface” Journal of Investigative Dermatology, 1983, vol. 81, No. 1 Supplement 1, pp. 28s-33s.
Berking et al, “Photocarcinogenesis in human adult skin grafts” Carcinogenesis, 2002, vol. 23, No. 1, pp. 181-187.
Makoto Tsunenaga, et al., “Organotypic Culture of Human Keratinocytes”, Tissue Culture, vol. 20, No. 8, 1994, pp. 282-285 (with English partial translation).
Makoto Tsunenaga, et al., “Growth and Differentiation Properties of Normal and Transformed Human Keratinocytes in Organotypic Culture”. Jpn. J. Cancer Res., vol. 85, No. 3, Mar. 1994, pp. 238-244.
Homg-Chin Yan, et al., “Human/Severe Combined Immunodeficient Mouse Chimeras an Experimental in Vivo Model system to Study the Regulation of Human Endothelial Cell-Leukocyte Adhesion Molecules”, The American Society for Clinical Investigation, Inc., vol. 91, No. 3, Mar. 1993, pp. 986-996.
C. Kathy Wang, et al., “Spontaneous Cell Sorting of Fibroblasts and Keratinocytes Creates an Organotypic Human Skin Equivalent”, The Society for Investigative Dermatology, Inc., vol. 114, No. 4, Apr. 2000, pp. 674-680.
Steven T. Boyce, et al., “Vitamin C Regulates Keratinocyte Viability, Epidermal Barrier, and Basement Membrane in Vitro, and Reduces Wound Contraction After Grafting of Cultured Skin Substitutes”, The Society for Investigative Dermatology, Inc., vol. 118, No. 4, Apr. 2002, 565-572.
Fusenig, N. E., et al., “Growth and Differentiation Characteristics of Transformed Keratinocytes from Mouse and Human Skin in Vitro and in Vivo,” The Journal of Investigative Dermatology, vol. 81, No. 1, Supplement, Jul. 1983, pp. 168s-175s.
Lichti, U., et al., “In Vivo Regulation of Murine Hair Growth: Insights from Grafting Defined Cell Populations onto Nude Mice,” The Journal of Investigative Dermatology, vol. 101, No. 1, Supplement, Jul. 1993, pp. 124S-129S.
Yuspa, S. H., et al., “The Growth of Fetal Mouse Skin in Cell Culture and Transplantation to F1Mice,” The Journal of Investigative Dermatology, vol. 55, No. 6, 1970, pp. 379-389.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for constructing reconstructed skin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for constructing reconstructed skin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for constructing reconstructed skin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4153202

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.