Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1994-08-12
1997-02-04
Feisee, Lila
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303888, 5303898, 5303894, 5303883, 53038822, 5303911, 5303913, 5303915, 5303917, C07K 1642
Patent
active
055999085
ABSTRACT:
Hybrid reagents comprising a first portion having an affinity for a cellular target and a second portion having an affinity for a bioactive molecule are described, said hybrid reagents being capable of selectively releasing the bioactive molecule in response to a change in pH. The hybrid reagents of the present invention can be used diagnostically or therapeutically.
REFERENCES:
Waldmann Science vol. 252 p. 1657, 1991.
Harris et al. Tibtech vol. 11 1993, p. 42.
Hird et al, Genes and Cancer Carney et al ed. p. 183 1990.
Boston Biomedical Research Institute
Feisee Lila
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