Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-05-01
1998-08-11
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
356345, 356346, 356359, 356363, C12Q 168, G01B 902, G01B 1100, G01T 345
Patent
active
057926107
ABSTRACT:
The invention relates to a method of identifying the individual autosomal and sex chromosomes of a human karyotype through the use of a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with one predetermined autosomal or sex chromosome of a human karyotype.
REFERENCES:
patent: 3924952 (1975-12-01), Marechal et al.
patent: 4410275 (1983-10-01), Shaw et al.
patent: 4529312 (1985-07-01), Pavlath et al.
patent: 4637722 (1987-01-01), Kim
patent: 4671658 (1987-06-01), Shaw et al.
patent: 4687330 (1987-08-01), Lefevre
patent: 4687732 (1987-08-01), Ward et al.
patent: 4711955 (1987-12-01), Ward et al.
patent: 4836676 (1989-06-01), Kim et al.
patent: 5108183 (1992-04-01), Fling et al.
patent: 5328824 (1994-07-01), Ward et al.
patent: 5449767 (1995-09-01), Ward et al.
patent: 5539517 (1996-07-01), Cabib et al.
Lewis, R. (1996). FISH technology ready to leap from lab to the clinic. Gen. Eng. News. 16(10):1,26.
Marx, J. (1996). New methods for expanding the chromosomal paint kit. Science. 273:430.
Travis, J. (1996). Bringing bold color to chromosomes. Science News. 149:215.
Lewis, R. (1996). Chromosome charting takes a giant step. Photonics Spectra. 30:48.
Schrock, E. (1996). Multicolor spectral karyotyping of human chromosomes. Science. 273:494-497.
Speicher, M.R. (1996). Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nature Genet. 12:368-375.
Cremer, T. et al., "Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomony 18 with probe L1.84." Hum. Genet. 74:346-352 (1986).
Cremer, T. et al., "Role of chromosome territories in the functional compartmentalization of the cell nucleus." In: Cold Spring Harbor Symposia on Quantitative Biology, vol. LVIII, pp. 777-792, Cold Spring Harbor Laboratory Press, NY (1994).
Dauwerse, J.G. et al., "Multiple colors by fluorescence in situ hybridization using ratio-labeled DNA probes create a molecular karyotype." Hum. Mol. Genet. 1:539-598 (1992).
du Manoir, S. et al., "Hardware and software requirements for quantitative analysis of comparative genomic hybridization." Cytometry 9:4-9 (1995).
du Manoir, S. et al., "Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization." Hum. Gent. 90:590-610 (1993).
Ernst, L.A. et al., "Cyanine dye labeling reagents for sulfhydryl groups." Cytometry 10:3-10 (1989).
Guan, X.Y. et al., "Coverage of chromosome 6 by chromosome microdisection: generation of 14 subregion-specific probes." Hum. Genetics 95:637-640 (1995).
Ledbetter, D.H., "Localisation of pseudohypoaldosteronism genes to chromosome 16p12.2-13.1 and 12p13.1-pter by homozygosity mapping." Hum. Mol. Genet. 5:293-299 (1992).
Lengauer, C. et al., "Chromosome bar codes produced by multicolor fluoresence in situ hybridization with multiple YAC clones and whole chromosome painting probes." Hum. Mol. Genet. 2:505-512 (1993).
Manuelidis, L. et al., "Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction." Chromosoma 96:397-410 (1988).
Mujumdar, R.B. et al., "Cyanine dye labeling reagents containing isothiocyanate group." Cytometry 10:11-19 (1989).
Nederlof, P.M. et al., "Multiple fluorescence in situ hybridization." Cytometry 11:126-131 (1990).
Nederlof, P.M. et al., "Three color fluorescence in situ hybridization for the simultaneous detection of multiple nucleic acid sequences." Cytometry 10:20-27 (1989).
Pinkel, D. et al., "Cytogenic analysis using quantitative, high sensitivity, fluorescence hybridization." Proc. Natl. Acad. Sci. (U.S.A.) 83:2934-2938 (1986).
Ried, T. et al., "Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy." Proc. Natl. Acad. Sci. (U.S.A.) 89:1388-1392 (1992).
Smith, T.G. et al., "Edge detection in images using Marr-Hildreth filtering techniques." J. Neurosci. Methods 2675-82 (1988).
Telenius, H. et al., "Cytogenic analysis by chromosome painting using DOP-PCR amplified flow-sorted chromosomes." Genes, Chromosomes & Cancer 4:257-263 (1992).
Waggoner, A., "Covalent labeling of proteins and nucleic acids with fluorophores." Methods in Enzymology 246:362-373 (1995).
Waggoner, A. et al., "Multiple spectral parameter imaging." Methods Cell Biol. 30:449-478 (1989).
Wiegant, J. et al., "Multiple and sensitive fluorescence in situ hybridization with rhodamine- , fluorescein- , and coumarin-labeled DNAs." Cytogenet. Cell Genet. 63:73-76 (1993).
Wiegant, J. et al., "In situ hybridization with fluoreceinated DNA." Nuc. Acids Res. 19:3237-3241 (1991).
Popp et al. (1993) Human Genetics 92:527-32.
Malik et al. (1996) Photochemistry and Photobiology 63:608-614.
Heffelfinger David M.
Witney Franklin R.
Atzel Amy
Auerbach Jeffrey I.
Bio-Rad Laboratories, Inc.
Jones W. Gary
LandOfFree
Method for conducting multiparametric fluorescence in situ hybri does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for conducting multiparametric fluorescence in situ hybri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for conducting multiparametric fluorescence in situ hybri will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-387888