Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1991-11-26
1994-03-01
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, 424 88, 424 91, 436829, A61K 3722
Patent
active
052905632
ABSTRACT:
In the method for combining with liposomes heterogeneous substances contained in a mixture, in particular, allergenic substances such as allergens and/or allergenic extracts, contained in an allergenic preparation, by adsorption on the surface of, and/or incorporation in, liposomes which comprise cholesterol, a phospholipid and/or at least one ionic lipid which gives the liposome a positive or negative charge, the liposome or its constituents are combined with the mixture of heterogeneous substances, the pH of the entire combination being higher or lower than the isoelectric point ip of the substances contained in the mixture, depending on whether the ionic lipid is charged positively or negatively respectively.
REFERENCES:
patent: 4164558 (1979-08-01), von Schulthess et al.
patent: 4578270 (1986-03-01), Csizer et al.
patent: 4590170 (1986-05-01), Akiyoshi et al.
patent: 4619794 (1986-10-01), Hauser
patent: 4762720 (1988-08-01), Jizomoto
patent: 4944948 (1990-07-01), Uster et al.
patent: 5013555 (1991-05-01), Collins
patent: 5047245 (1991-09-01), Bally et al.
patent: 5049390 (1991-09-01), Wojdani
Mayer et al, "Techniques For Encapsulating Bioactive Agents Into Liposomes", Chemistry And Physics Of Lipids, 40(1986): pp. 333-345.
Morrison T. M., Boyd R. N. Organic Chemistry. 3rd ED. Boston, Allyn & Bacon 1973 pp. 1137-1138; 1151-1152.
Millet-Genin Isabelle
Puisieux Francis
Roblot-Treupel Liliane
Thao Tran X.
Harrison Robert H.
Laboratoire Des Stallergenes
Page Thurman K.
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