Method for combating virus infection

Details Method for combating virus infection Method for combating virus infection

1985-10-31

1988-09-13

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

A61K 3166

Patent

active

047710411

ABSTRACT:
A method for the selective treatment of virus infections in animals and man comprising administering to a host so infected a therapeutically effective amount of phosphonoformic acid or a physiologically acceptable salt thereof.

REFERENCES:
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Beilstein E 111e, p. 240, (1961).
Chemical Abstracts, 83:73487n, (1975).
Nagvi et al., J. Chem. Soc. (A), 2751-2754, (1971).
Warren et al., J. Chem. Soc. (B), 618-621, (1971).
"Soon a Drug Against Aids will be Available", Arbet, Nov. 2, 1984, (including translation).
Oxford et al., "Conquest of Viral Diseases", May 1, 1985, Elsevier Science Publishers B.V., p. 591.
Sandstrom et al., "Inhibition of Human T-Cell Lymphotropic Virus Type III in Vitro by Phosphonoformate", The Lancet, Jun. 29, 1985, pp. 1480-1482.
Seligmann et al., "Aids--An Immunologic Reevaluation", The New England Journal of Medicine, vol. 311, No. 20, Nov. 15, 1984, pp. 1286-1291.
Montagnier et al., "Lymphadenopathy Associated Virus and AIDS", Clinical Immunology Newsletter, vol. 6, No. 5, May, 1985, pp. 65-68.

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