Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-07-12
1998-11-03
Saunders, David
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
436 87, 436 94, 436161, 436177, 436509, 436824, G01N 3348
Patent
active
058310371
ABSTRACT:
The present invention relates to a novel clinical examination method which comprises analyzing the alteration in the amount of a specific component in oligosaccharides of immunogloblin G. Human diseases such as liver diseases, malignant hypertension, immunogloblin A-nephropathy, pediatric disorders, etc., are examined in terms of the alteration in bisecting N-acetylglucosamine-containing oligosaccharides in immunogloblin G from collected humor. The present invention provides highly accurate information in a manner applicable to practical operation for examination of liver diseases, allergic diseases, malignant hypertension, immunogloblin A nephropathy, pediatric disorders, as well as aging-dependent variations and the therapeutic effect of interferon.
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Biochemistry and Molecular Biology International, vol. 32, No. 5, pp. 897-902, Apr. 1994, A. Kondo, et al., "Analysis of Oligosaccharides of Human IgG from Serum of Leukemia Patients".
Fujimori Masahiro
Ishida Chizu
Kawamura Yoshiya
Kibe Tetsuya
Mizokami Masashi
Nakano Vinegar Co., Ltd.
Saunders David
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