Method for characterizing autoimmune disorders

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007920, C435S973000, C436S506000, C436S518000, C436S523000, C436S524000

Reexamination Certificate

active

10222867

ABSTRACT:
The invention relates to methods of characterizing autoimmune diseases by detecting and measuring at least one analyte using multiplexed assay systems. According to one embodiment, a target is detected and measured by different bead sets having different reactants. According to another approach the ratio of self-antigen to autoantibody is measured by exposing a sample suspected of containing self-antigen and autoantibody to a bead set associated with monoclonal antibody specific for the self-antigen and a bead set associated with the self-antigen.

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International Search Report, International Application No. PCT/US02/26267, International Filing Date Aug. 19, 2002.

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