Method for carrying out-CC-coupling reactions

Chemistry of hydrocarbon compounds – Aromatic compound synthesis – By condensation of entire cyclic molecules or entire...

Reexamination Certificate

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C585S425000, C585S427000

Reexamination Certificate

active

07102045

ABSTRACT:
The invention relates to a method for carrying out CC-coupling reactions, in particular a Heck and Suzuki reaction, in the presence of supported palladium as the catalyst and a base in a monophase or multiphase solvent mixture. According to said method, palladium detaches itself from the support in a characteristic manner, is redeposited after the reaction and the quantity of palladium not deposited after the reaction is significantly lower than 5000 ppm, in relation to the palladium used.

REFERENCES:
patent: 42 36 103 (1994-04-01), None
patent: 0 509 426 (1992-10-01), None
Marck et al, Tetrahedron Letters, (1994), vol.35 (20) pp. 3277-3280.
Blaser et al, Supported palladium catalysts for fine chemicals synthesis, Journal of Molecular Catalysis A: Chemical vol. 173 (2001) 3-18.
G. Marck, “Aryl couplings with heterogeneous palladium catalysts”, Tetrahedron Letters, 1994, pp. 3277-3280, vol. 35, and No. 20.
M. Julia, “Etude de la condensation de chlorures aromatiques avec les oléfines catalysée par le palladium”, Bulletin De La Societe Chimique De France, 1973, pp. 2791-2794 and No. 9-10.

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