Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1994-08-02
1996-07-30
Warden, Robert J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
530334, 530335, 525 5411, C07H 2100, C07K 106
Patent
active
055413145
ABSTRACT:
Apparatus and method for the automated synthesis of DNA segments utilizing multiple reaction columns, all of which are open at the inlet end to the atmosphere of a reaction chamber. A movable reagent supply line outlet is positioned adjacent to the column inlet end to apply reagent to each of the columns according to an input sequence of delivery. The delivery sequence is under processor control. Reagents are removed from all columns simultaneously through the application of vacuum at the outlet end of each column. The device enables the parallel synthesis of large numbers of different oligonucleotide sequences of different lengths.
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Grosse William M.
McGraw Royal A.
Snider Theresa T.
University of Georgia Research Foundation Inc.
Warden Robert J.
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