Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;...
Reexamination Certificate
2006-10-17
2006-10-17
Naff, David M. (Department: 1651)
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
C424S178100, C424S094100, C435S176000, C435S177000, C435S180000, C435S181000, C436S518000, C436S524000, C436S531000, C436S532000, C530S402000, C530S810000, C530S811000, C530S812000, C530S816000
Reexamination Certificate
active
07122356
ABSTRACT:
A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.
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Keogh James R.
Trescony Paul V.
Collier Kenneth J.
Medtronic Inc.
Naff David M.
Ruschke David P.
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