Method for assisting normal breathing in a mammal having a lung

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Halogenated hydrocarbon doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514722, 514756, 514832, 514833, A61K 31025

Patent

active

056749139

ABSTRACT:
A method of assisting a mammal having a lung disorder to breathe ambient gas normally, i.e., without the assistance of a ventilator. The method includes providing an animal having a lung disorder, such as surfactant deficiency, stiff lung or hyperinflated lung syndrome, and instilling a perfluorochemical liquid into the trachea for administration in the alveolar sacs of a lung of the animal. The perfluorochemical is permeable to the ambient gas and resides substantially permanently within the alveolar sacs without inducing hyperinflated lung syndrome. The liquid is instilled in an amount sufficient to enable the animal to breathe the ambient gas normally with O.sub.2 /CO.sub.2 blood gas exchange. In another aspect of the invention, the method further includes the step of alleviating the lung disorder without inducing hyperinflated lung syndrome.

REFERENCES:
patent: 3911138 (1975-10-01), Clark, Jr.
patent: 4173654 (1979-11-01), Scherer
patent: 5158536 (1992-10-01), Sekins et al.
patent: 5295953 (1994-03-01), Richard et al.
patent: 5300528 (1994-04-01), Graybill et al.
patent: 5437272 (1995-08-01), Fuhrman
patent: 5490498 (1996-02-01), Faithfull
Leach, C. L. et al., Critical Care Medicine, "Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: A prospective, randomized, controlled study", vol. 21, No. 9, .COPYRGT.1993 by Williams & Wilkins.
Tutuncu, A. S. et al., American Review of Respiratory Disease, "Comparison Ventilatory Support with Intratracheal Perfluorocarbon Administration and Conventional . . . Acute Respiratory Failure", vol. 148, pp. 785-792, (1993).
Hoffmann, R. E. et al., Biomat., Art. Cells & Immob. Biotech., "Arterial Blood Gases and Brian Oxygen Availability Following Infusion of Intratracheal Fluorocarbon Neat Liquid", 20 (2-4), 1073-1083, .COPYRGT.1992 by Marcel Dekker, Inc.
Clark, L. C., Jr. et al., Biomat., Art. Cells & Immob. Biotech., "Response of the Rabbit Lung as a Criterion of Safety for Fluorocarbon Breathing and Blood Substitutes", 20 (2-4), 1085-1099, .COPYRGT.1992 by Marcel Dekker, Inc.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for assisting normal breathing in a mammal having a lung does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for assisting normal breathing in a mammal having a lung , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for assisting normal breathing in a mammal having a lung will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2357801

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.