Method for assessing the risk of peptic ulcer, comprising...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007230, C435S004000, C435S007100, C435S007400, C435S007700, C435S007720, C435S007910, C435S006120, C435S252300, C530S388100, C530S388400, C530S388700, C530S350000, C530S387100

Reexamination Certificate

active

06872543

ABSTRACT:
The present invention concerns a method for assessing the risk of peptic ulcer by determining the presence and topographic phenotype of gastritis in an individual, by determining quantitatively the pepsinogen I and gastin-17 concentrations in a serum sample from the said individual, selecting a method-specific reference value and cut-off value for respective analyte, assessing the topography and phenotype of gastritis based on a comparison of the pepsinogen I and gastrin-17 concentrations so determined with their respective method-specific reference and cut-off values, and correlating the so assessed gastritis phenotype with the risk for peptic ulcer. Preferably alsoHelicobacterantibodies are determined in the sample.

REFERENCES:
patent: 6156525 (2000-12-01), Furuta
patent: 9615456 (1996-05-01), None
patent: 9615456 (1996-05-01), None
Ardrill, J et al, Regulatory Peptides, 1992, vol. 40(2), Jul. 23, p. P109, abstract only.*
Chen, Tseng-Shing et al, The American Joural of Gastroenterology, vol. 89(9), pp. 1511-1514, 1994.*
Hallissey, MT et al, Scandinavian Journal of GAstroenterology, vol. 29(12), pp. 1129-1134, Dec. 1994.*
Kekki, M et al, Scan Journal of Gastroenterology, vol. 26 (suppl. 186), pp. 109-116, 1991, Serum pepsinogen-I and Serum Gastrin in the screening of Severe atrophic corpus gastritis.*
Malfertheiner, P et al, Eur. J. Gastroenterol. Hepatol., 1993, vol. 5(suppl. 1), pp. S1-S8,Helicobacter pyloriand the pathogenesis of duodenal ulcer disease.*
Mulholland, G et al, Gut (England), Jun. 1993, vol. 34(6), pp. 757-761,Helicobacter pylorirelated hypergastinaemia is the result of a selective increase in gastrin-17.*
Petersen, B et al, Scand. J. Gastroenterol., vol. 18(5), pp. 635-642, Increased concentrations of the amino terminal fragment of gastrin-17 in acute duodenal ulcer and acute gastritis.*
Petersen,B, Scand. J. Gastroenterol.(Norway), 1983, vol. 18(5), pp. 613-617, Metabolism of the NH2-terminal tridecapeptide of gastrin-17 in normal subjects and duodenal ulcer patients.*
Pilotto, A et al, J. Am. Geriatr. Soc., vol. 44, pp. 665-670, 1996.*
Plebani, M, Crit. Rev. Clin. Lab. Sci, 1993, vol. 30(3), pp. 273-328, Pepsinogens in health and Disease.*
Walker, K et al, Clin. Ther. vol. 7(6), pp. 704-716, 1985.*
Westerveld, BD et al, Cancer, Mar. 1, 1987, Vo.l. 59(5), pp. 952-958.*
Westerveld, BD et al, Prog. Clin. Biol. Res., 1985, vol. 173, pp. 201-212.*
Valle, J et al, Eur. J. of Gastroenterol. and Hepatol., vol. 4 (12), pp. 985-989, 1992.*
Wu, M-S et al, Am. J. of Gastroenterology, vol. 89(8), p. 1361, 1994, abstract No. 304, (abstract only).*
Roll, J et al, Arch Intern. Med. vol. 157, May 12, 1997, pp. 994-998, Diagnosis and Treatment ofHelicobacter pyloriinfection among California Medicare Patients.*
The American Journal of Gastroenterology, vol. 89, No 9, 1994, Tseng-Shing Chen, M.D. et al, “effect of Eradiction ofHelicobacter pylorion Serum Pepsinogen I, Gastrin, and Insulin in Duodenal Ulcer Patients: A 12-month Follow-up Study” p. 1511-p. 1514.
European Journal of Gastroenterology & Hepatology, vol. 11, 1999, Javier P. Gisbert et al, “Basal and stimulated gastrin and pepsinogen levels after eradicaion ofHelicobacter pylori: a 1-year follow-up study” p. 189-p. 200.

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