Method for assaying vitamin-containing compositions for vitamin

Details Method for assaying vitamin-containing compositions for vitamin Method for assaying vitamin-containing compositions for vitamin

1981-08-13

1984-01-24

Nucker, Christine M.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

Utilizing isolate of tissue or organ as binding agent

436542, 436177, 436804, 436822, G01N 3358, G01N 3360

Patent

active

044277806

ABSTRACT:
Vitamin-containing multicomponent compositions are assayed to determine the extent of conversion of the vitamin to one or more analogues thereof due to interaction between the vitamin and the other components of the composition, employing a radioactive labeled form of the vitamin. The assay is useful for quality control in the manufacture of multivitamin and multivitamin-mineral formulations and vitamin-supplemented foods intended for human or animal ingestion.

REFERENCES:
patent: 4188189 (1980-02-01), Allen
patent: 4332786 (1982-06-01), Cabelli et al.
patent: 4333918 (1982-06-01), Carney et al.
Kolhouse et al., N. Eng. J. Med., 299(15), 785-792 (1978).
LeFebvre et al., Chemical Abstracts, 93(21), 1980, #200436d.
Rothenberg, Chemical Abstracts, 94(17), 1981, #131819n.
Kolhouse et al., J. Clin. Invest., 60(6), 1381-1392 (1977).
Kolhouse et al., Chemical Abstracts, 88(13), 1978, #85428k.

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