Chemistry: analytical and immunological testing – Optical result
Patent
1996-12-31
1999-03-16
Wallenhorst, Maureen M.
Chemistry: analytical and immunological testing
Optical result
436179, 356 39, 356317, 356318, 600310, 600322, 600476, 600477, G01N 2100
Patent
active
058829407
ABSTRACT:
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of drawing a blood sample from the patient, separating a blood plasma portion from the blood sample, irradiating the blood plasma portion with an interrogation light at an interrogation wavelength range at an absorption band bluer than the treatment light wavelength, measuring a magnitude of an emission signal at the treatment light wavelength, the emission signal caused by the irradiation of the blood plasma portion, and comparing the measured magnitude to a magnitude/concentration calibration curve to determine the concentration of the photosensitizing drug.
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Ronn et al. "Interspecies Pharmacokinetics . . . " Proceedings of SPIE, vol. 2625, pp. 118-123, 1996.
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Lee Shu Muk
Pastel Christopher R.
Wallenhorst Maureen M.
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