Method for ascertaining the history of a condition of the body f

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 2, 435 6, 435 14, 435 15, 424 11, 436 63, 436 67, 436 70, 436 72, 436 94, 436174, 436501, 436520, 436827, 436811, C12Q 100, C12Q 154

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048350974

ABSTRACT:
A historical time series analysis is obtained from a single sample of blood by measurement of hemoglobin and an altered hemoglobin, for example, glycohemoglobin, on a cell-by-cell basis. The results are compared by ratio of glycohemoglobin to hemoglobin on a cell-by-cell basis. Since the alteration of hemoglobin is continuous and irreversible, the ordered set of ratios represents a time-series of the cells, and any deviation from normal will be readily apparent A time-series can also be derived for other constituents, the time-series representing historical data of the other constituents in the person from whom the blood sample was taken.

REFERENCES:
Bartosz, G., Biochemical Medicine, 27:398-400 (1982).
Elseweidy M. M. et al., Hemoglobin, 8(4): 363-372 (1984).
Rigal, D. et al, La Presse Medicale, 14, No. 9: 521-523 (3-1985).

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