Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1986-10-15
1989-05-30
Moskowitz, Margaret
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435 2, 435 6, 435 14, 435 15, 424 11, 436 63, 436 67, 436 70, 436 72, 436 94, 436174, 436501, 436520, 436827, 436811, C12Q 100, C12Q 154
Patent
active
048350974
ABSTRACT:
A historical time series analysis is obtained from a single sample of blood by measurement of hemoglobin and an altered hemoglobin, for example, glycohemoglobin, on a cell-by-cell basis. The results are compared by ratio of glycohemoglobin to hemoglobin on a cell-by-cell basis. Since the alteration of hemoglobin is continuous and irreversible, the ordered set of ratios represents a time-series of the cells, and any deviation from normal will be readily apparent A time-series can also be derived for other constituents, the time-series representing historical data of the other constituents in the person from whom the blood sample was taken.
REFERENCES:
Bartosz, G., Biochemical Medicine, 27:398-400 (1982).
Elseweidy M. M. et al., Hemoglobin, 8(4): 363-372 (1984).
Rigal, D. et al, La Presse Medicale, 14, No. 9: 521-523 (3-1985).
Cooper Iver P
Moskowitz Margaret
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