Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;...
Reexamination Certificate
2005-05-17
2005-05-17
Redding, David A. (Department: 1744)
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
C435S180000, C435S395000, C436S524000, C436S527000
Reexamination Certificate
active
06893851
ABSTRACT:
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in fluid-tight contact with the support, the first layer having an upper surface and defining a pattern of micro-orifices, each micro-orifice of the pattern of micro-orifices having walls and defining a micro-region on the support when the first layer is placed in fluid-tight contact with the support such that the walls of said each micro-orifice and the micro-region on the support together define a micro-well; and a second layer configured to be placed in fluid-tight contact with the upper surface of the first layer, the second layer defining a pattern of macro-orifices, each macro-orifice of the pattern of macro-orifices having walls and defining a macro-region when the first layer is placed in fluid-tight contact with the support and the second layer is placed in fluid-tight contact with the first layer such that the walls of the macro-orifice and the macro-region together define a macro-well.
REFERENCES:
patent: 4240751 (1980-12-01), Linnecke et al.
patent: 4728591 (1988-03-01), Clark et al.
patent: 4789601 (1988-12-01), Banes
patent: 4802951 (1989-02-01), Clark et al.
patent: 4831869 (1989-05-01), Fowler
patent: 4842633 (1989-06-01), Kuribayashi et al.
patent: 4912057 (1990-03-01), Guirguis
patent: 4999489 (1991-03-01), Huggins
patent: 5072382 (1991-12-01), Kamentsky
patent: 5079600 (1992-01-01), Schnur et al.
patent: 5120662 (1992-06-01), Chan et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5202227 (1993-04-01), Matsuda et al.
patent: 5224058 (1993-06-01), Mickaels et al.
patent: 5278063 (1994-01-01), Hubbell et al.
patent: 5312731 (1994-05-01), Engstrom
patent: 5324591 (1994-06-01), Georger, Jr. et al.
patent: 5330911 (1994-07-01), Hubbell et al.
patent: 5424213 (1995-06-01), Mougin
patent: 5427663 (1995-06-01), Austin
patent: 5470739 (1995-11-01), Akaike et al.
patent: 5492890 (1996-02-01), Ginsberg et al.
patent: 5510481 (1996-04-01), Bednarski et al.
patent: 5512131 (1996-04-01), Kumar et al.
patent: 5514501 (1996-05-01), Tarlov
patent: 5573942 (1996-11-01), Miyamoto
patent: 5591627 (1997-01-01), Miyamoto
patent: 5599695 (1997-02-01), Pease et al.
patent: 5602029 (1997-02-01), Miyamoto
patent: 5679310 (1997-10-01), Manns
patent: 5691018 (1997-11-01), Kelley et al.
patent: 5719060 (1998-02-01), Hutchens et al.
patent: 5721131 (1998-02-01), Rudolph et al.
patent: 5744366 (1998-04-01), Kricka et al.
patent: 5776748 (1998-07-01), Singhvi et al.
patent: 5828776 (1998-10-01), Lee et al.
patent: 5840256 (1998-11-01), Demers et al.
patent: 5856082 (1999-01-01), Aebersold et al.
patent: 5858801 (1999-01-01), Brizzolara
patent: 5866321 (1999-02-01), Matsue
patent: 5894063 (1999-04-01), Hutchens et al.
patent: 5900160 (1999-05-01), Whitesides et al.
patent: 5935850 (1999-08-01), Clark et al.
patent: 5942443 (1999-08-01), Parce et al.
patent: 5976826 (1999-11-01), Singhvi et al.
patent: 5989835 (1999-11-01), Dunlay et al.
patent: 6001556 (1999-12-01), Charych et al.
patent: 6008010 (1999-12-01), Greenberger et al.
patent: 6020208 (2000-02-01), Hutchens et al.
patent: 6027942 (2000-02-01), Hutchens et al.
patent: 6037171 (2000-03-01), Larsson
patent: 6039897 (2000-03-01), Lochhead et al.
patent: 6071610 (2000-06-01), Jarrell et al.
patent: 6096510 (2000-08-01), Hochman
patent: 6100043 (2000-08-01), Bridgham et al.
patent: 6103479 (2000-08-01), Taylor
patent: 6127129 (2000-10-01), Corn et al.
patent: 6133030 (2000-10-01), Bhatia et al.
patent: 6136592 (2000-10-01), Leighton et al.
patent: 6140045 (2000-10-01), Wholstadter et al.
patent: 6143247 (2000-11-01), Sheepard, Jr. et al.
patent: 6180239 (2001-01-01), Whitesides et al.
patent: 6207369 (2001-03-01), Wohlstadter
patent: 6221579 (2001-04-01), Everhart et al.
patent: 6238874 (2001-05-01), Jarnagin et al.
patent: 6251672 (2001-06-01), Kubbies et al.
patent: 6270980 (2001-08-01), Fritz et al.
patent: 6280967 (2001-08-01), Ransom
patent: 6329164 (2001-12-01), Goodwin, Jr. et al.
patent: 6368877 (2002-04-01), Zhang et al.
patent: 6558904 (2003-05-01), Ermantraut et al.
patent: 1 199 354 (2002-03-01), None
patent: WO 9836827 (1998-08-01), None
patent: WO 9838490 (1998-09-01), None
patent: WO 9858967 (1998-12-01), None
patent: WO 9954786 (1999-10-01), None
patent: WO 0060356 (2000-10-01), None
patent: WO 0067028 (2000-11-01), None
patent: 2001 0001644 (2001-05-01), None
patent: WO 0170389 (2001-09-01), None
patent: 2001 0053527 (2001-12-01), None
patent: WO 0204113 (2002-01-01), None
patent: 2002 0012953 (2002-01-01), None
Bernard et al., “Printing Patterns of Proteins”, Langmuir, Apr. 28, 1998, vol. 14, No. 9, pp. 2226-2228.
Branch et al., “Microstamp patterns of biomolecules for high-resolution neuronal networks”, Medical & Biological Engineering & Computing, 1998, vol. 36, pp. 135-141.
Duffy et al., “Patterning Electroluminscent Materials with Feature Sizes as Small as 5 μm Using Elastromeric Membranes as Masks for Dry Lift-Off”, Advanced Materials, vol. 11 No. 7, pp. 546 552.
Folch et al., “Cellular Micropatterns on Biocompatible Materials”, Biotechol. Prog., 1998, vol. 14 No. 3, pp. 388-392.
Gonzalez et al., “Intracellular detection assays for high-throughout screening”, Current Opinion in Biotechnology, 1998, 9:624-631.
Hale,“Irreversible, Oriented Immobilization of Antibodies to Cobalt-Iminodiacetate Resin for Use as Immunoaffinity Media”, Analytical Biochemistry, 1995, 231, 46-49.
Kind et al., “Patterned Electroless Deposition of Copper by Microcontact Printing Palladium (II) Complexes on Titanium-Covered Surfaces” Langmuir, Aug. 8, 2000, vol. 16, N. 16, pp. 6367-6373.
Jackman et al., “Using Elastomeric Membranes as Dry Resists and for Dry Lift-Off”, Langmuir, 1999, vol. 15, pp. 2973-2984.
Jackman et al., “Fabricating Large Arrays of Microwells with Arbitrary Dimensions and Filling Them Using Discontinuous Dewetting”, Anal. Chem., 1998, 2280-2287.
Mere et al, “Miniaturized FRET assays and microfluidics: key components for ultra-high throughput screening”, DDT, Aug. 8, 1999, vol. 4 363-369.
Saleemuddin, “Bioaffinity Based Immobilization of Enzymes”, Advances in Biochemical Engineering/Biotechnology, 1999, vol. 64. pp. 204-226.
Sigal et al., “A Self-Assembled Monolayer for the Binding and Study of Histidine-Tagged Proteins by Surface Plasmon Resonance”, Anal. Chem. 1996, 68, 490-497.
Sigal et al., “Using Surface Plasmon Resonance Spectroscopy To Measure the Association of Detergents with Self-Assembled Monolayers of Hexadecanethiolate on Gold”, Langmuir, 1997, 13, pp. 2749-2755.
Sittampalam et al, “High-throughput screening: advances in assay technologies”, Current Opinion in Chemical Biology, 1997, 1:384-391.
Xia et al., “Soft Lithography”, Angew. Chem. Ins. Ed., 1998, vol. 37, pp. 551-575.
Bhatia et al. “Probing heterotypic cell interactions: Hepatocyte function in microfabricated co-cultures,” Science Polyner Edition, vol. 9, No. 11, pp.1137-1160 (1998).
Bhatia et al., “Selective Adhesion of Hepatocytes on Patterned Surfaces,” Annals of the New York Academy of Science, vol. 745,pp. 187-209 (1994).
Bhatia et al., “Effect of cell—cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells,” The FASEB Journal, vol. 13, pp. 1883-1900 (1999.
Chen et al., “Using Self-Assembled Monolayers to Pattern ECM Proteins and Cells on Substrates,” Methods In Molecular Biology—Extracellular, Matrix Protocols, pp. 209-218.
Chen et al., “Micropatterned Surfaces for Control of Cell Shape, Position, and Function,” 1998 Biotechnol, Prog. 1998, vol. 14, pp. 356-3643.
Duffy et al., “Multiplexed Kinase As
Kim Enoch
Kirk Gregory L.
Ostuni Emanuele
Schueller Olivier
Kenyon & Kenyon
Redding David A.
Surface Logix Inc.
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