Method for arranging a polynucleotide on a substrate for point-b

Details Method for arranging a polynucleotide on a substrate for point-b Method for arranging a polynucleotide on a substrate for point-b

1994-07-29

1997-03-18

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 254, C12Q 168, G01N 3324

Patent

active

056121814

ABSTRACT:
The invention relates to a method for arranging a polynucleotide on a substrate for point-by-point analysis of each successive base. It includes in combination anchoring the polynucleotide towards one end to a precise location on a substrate, and stretching out the polynucleotide, in view of conducting a point-by-point analysis of the polynucleotide arranged on said surface.

REFERENCES:
Journal of Vacuum Science & Technology/Section A vol. 6, No. 3, part II, "Atomic force microscopy and scanning tunneling microscopy with a combination atomic force microscope/scanning tunneling microscope".
Soviet Technical Physics Letters, vol. 13, No. 8, pp. 387-393.

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