Method for androgen supplementation

Details Method for androgen supplementation Method for androgen supplementation

1992-10-15

1994-08-30

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514179, A61K 3156

Patent

active

053428340

ABSTRACT:
A particular group of androgens is not metabolized to their 5.alpha.-reduced form in the prostate and other tissues. Thus, administration of these compounds--testosterone derivatives with a non-hydrogen substituent in the 6.alpha. or 7.alpha. position--allows one to provide androgen supplementation therapy without stimulating abnormal prostate growth. A preferred compound for use in the invention is 7.alpha.-methyl-19-nortestosterone.

REFERENCES:
patent: 3341557 (1967-09-01), Babcock et al.
patent: 4412993 (1983-11-01), Sokolowski
patent: 4701450 (1987-10-01), Kelder et al.
Endocrinology, vol. 119, No. 3 pp. 959-966; Blohm et al., 1986.
Androgens and Anabolic Agents (1969) pp. 1, 2, 19, 59-62, 77-78; Vida.
"In vitro Metabolism of 7-.alpha.alpha -methyl-19-Nortestosterone by Rat Liver, Prostate, and Epididymis", A. K. Agarwal and C. Monder, Endocrinology, vol. 123, No. 5, 1988, pp. 2187-2193.

Affiliated with

Also associated with

Rating

Method for androgen supplementation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for androgen supplementation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for androgen supplementation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-30082