Method for analyzing proteins

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07867755

ABSTRACT:
A method for analyzing proteins makes use of an array of first capture molecules which are specific for peptide epitopes. The proteins to be analyzed or a protein mixture containing the proteins to be analyzed is degraded to peptide fragments corresponding to the peptide epitopes, after which the array of capture molecules is incubated with the peptide fragments. The peptide fragments bound to the capture molecules are then detected.

REFERENCES:
patent: 4478744 (1984-10-01), Mezei et al.
patent: 4658022 (1987-04-01), Knowles et al.
patent: 4970171 (1990-11-01), Messenger et al.
patent: 5061790 (1991-10-01), Elting et al.
patent: 5223441 (1993-06-01), Ullman et al.
patent: 5449601 (1995-09-01), Jean et al.
patent: 5565332 (1996-10-01), Hoogenboom et al.
patent: 5708155 (1998-01-01), Potter et al.
patent: 5723129 (1998-03-01), Potter et al.
patent: 5763158 (1998-06-01), Bohannon
patent: 5790155 (1998-08-01), Usui et al.
patent: 5798155 (1998-08-01), Yanagawa et al.
patent: 5849531 (1998-12-01), Potter
patent: 5872234 (1999-02-01), Bandman et al.
patent: 5955317 (1999-09-01), Suzuki et al.
patent: 5961923 (1999-10-01), Nova et al.
patent: 6113897 (2000-09-01), Dano et al.
patent: 6197599 (2001-03-01), Chin et al.
patent: 6225047 (2001-05-01), Hutchens et al.
patent: 6261569 (2001-07-01), Comis et al.
patent: 6329209 (2001-12-01), Wagner et al.
patent: 6365418 (2002-04-01), Wagner et al.
patent: 6406921 (2002-06-01), Wagner et al.
patent: 6420125 (2002-07-01), Fledelius et al.
patent: 6794363 (2004-09-01), Bejanin et al.
patent: 6897073 (2005-05-01), Wagner et al.
patent: 6955915 (2005-10-01), Fodor et al.
patent: 7022486 (2006-04-01), Campbell
patent: 7645586 (2010-01-01), Gordon et al.
patent: 2002/0042386 (2002-04-01), Rosen et al.
patent: 2002/0055186 (2002-05-01), Barry et al.
patent: 2002/0081617 (2002-06-01), Buranda et al.
patent: 2002/0106702 (2002-08-01), Wagner et al.
patent: 2002/0110843 (2002-08-01), Dumas
patent: 2002/0110933 (2002-08-01), Wagner et al.
patent: 2002/0119579 (2002-08-01), Wagner
patent: 2002/0137119 (2002-09-01), Katz
patent: 2003/0028330 (2003-02-01), Cheng et al.
patent: 2003/0032039 (2003-02-01), Cunningham et al.
patent: 2003/0044862 (2003-03-01), Giaccia et al.
patent: 2003/0054408 (2003-03-01), Ravi et al.
patent: 2003/0143612 (2003-07-01), Ault-Riche et al.
patent: 2004/0029292 (2004-02-01), Joos et al.
patent: 2004/0229284 (2004-11-01), Luciw et al.
patent: 2005/0153298 (2005-07-01), Gembitsky et al.
patent: 2005/0214304 (2005-09-01), Pastan et al.
patent: 40 23 945 (1992-01-01), None
patent: 0 267 355 (1987-03-01), None
patent: 0 337 057 (1989-01-01), None
patent: 07285999 (1995-10-01), None
patent: WO 96/05847 (1996-02-01), None
patent: WO-96/05847 (1996-02-01), None
patent: WO-96/29629 (1996-09-01), None
patent: WO-97/07132 (1997-02-01), None
patent: WO-99/38013 (1999-07-01), None
patent: WO-9939210 (1999-08-01), None
patent: WO-00/04389 (2000-01-01), None
patent: WO-00/04389 (2000-04-01), None
patent: WO 00/45168 (2000-08-01), None
patent: WO-00/45168 (2000-08-01), None
patent: WO-00/54046 (2000-09-01), None
patent: WO-01/78652 (2001-10-01), None
patent: WO-0206834 (2002-01-01), None
patent: WO-02/25287 (2002-03-01), None
patent: WO-03/058249 (2003-07-01), None
Shea EA & Cohen MP, Immunologic detection and measurement of glycated apolipoprotein B with site specific monoclonal antibodies. J. Immunol. Methods. Jun. 1993;162(1):85-95.
Maggio ET. Enzyme-immunoassay, pp. 53-70, CRC Press, Inc., (1980).
Harper et al., Two-Dimensional Gel Electrophoresis, Unit 10.4, Current Protocols in Protein Science (1998), pp. 10.4.1 to 10.4.36.
Maggio, E.T. Enzyme-Immunoassay, Chapters 3 and 9, CRC Press, Inc. (1980). (pp. 53-70 and 181-196).
Chou et al., “Prediction of Protein Conformation,”Biochemistry, vol. 13, No. 2, pp. 222-245, (1974).
Devereux et al., “A comprehensive set of sequence analysis programs for the VAX”,Nucleic Acids Research, vol. 12, No. 1, pp. 387-395, (1984).
Geng et al., “Signature-peptide approach to detecting proteins in complex mixtures,”Journal of Chromatography, vol. 870, pp. 295-313, (2000).
Grimm et al., “Nanogram scale separations of proteins using capillary high-performance liquid chromatography with fully-automated on-line microfraction collection followed by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry, protein sequencing and Western blot analysis.”Journal of Chromatographyvol. 800, pp. 83-88, (1998).
Hennig, WinPep-ein Programm zur Analyse von Aminosäuresequenzen,Biospektrum, vol. 4, No. 5, pp. 49-50 (1998).
Hopp et al., “A Computer Program for Predicting Protein Antigenic Determinants,”Molecular Immunology, vol. 20, No. 4, pp. 483-489, (1983).
Jean et al., “A novel protein immunoassay with predetermined specificity using monoclonal antibodies against tryptic fragments: application to HIV P24 antigen,”Journal of Immunological Methods, vol. 185, pp. 103-114, (1995).
Kyte et al., “A Simple Method for Displaying the Hydropathic Character of a Protein,”J. Mol. Biol., vol. 157, pp. 105-132, (1982).
Levilliers Nicolette et al., “Monoclonal and polyclonal antibodies detect a new type of post-translational modification of axonemal tubulin.”Journal of Cell Science, vol. 108, No. 9, pp. 3013-3028, (1995).
Phelps et al., Metabolomics and Microarrays for Improved Understanding of Phenotypic Characteristics Controlled by Both Genomics and Environmental Constraints. Curr. Opi. Biotech. 13(1): 20-24, 2002.
Arnheiter et al., Physicochemical and Antigenic Properties of Synthetic Fragments of Human Leukocyte Interferon. Nature 294: 278-280, 1981.
Arnon, R., Synthetic Peptides as the Basis for Vaccine Design. Molecular Immunology 28(3): 209-215, 1991.
Barbas III et al., Assembly of Combinatorial Antibody Libraries on Phage Surfaces: The Gene III Site. Proc. Natl. Acad. Sci. USA 88: 7978-7982, 1991.
Bittner et al., Molecular Classification of Cutaneous mMlignant Melanoma by Gene Expression Profiling. Nature 406: 536-40, 2000.
Borrebaeck, Antibodies in Diagnostics-From Immunoassays to Protein Chips. Immunology Today 21(8): 379-381, 2000.
Cazares et al., Discovery of prostate Cancer Biomarkers from Lazer Capture Microdissected (LCM) Cells Using Innovative Proteinchip SELDI Mass Spectroscopy. Proc. of the Annual Meeting of the American Association for Cancer Research, New York, NY, p. 851 (2000).
Chames et al., Antibody Engineering and its Applications in Tumor Targeting and Intracellular Immunization. FEMS Microbiology Letters 189: 1-8, 2000.
Clark et al., Genomic Analysis of Metastasis Reveals An Essential Role for RhoC. Nature 406: 532-35, 2000.
Evans et al., Effect of Anticoagulants and Storage Temperatures on Stability of Plasma and Serum Hormones. Clinical Biochemistry 34: 107-12, 2001.
Haab et al. Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions.Genome Biol. 2, RESEARCH0004.1-RESEARCH0004.13, 2001.
Haupt et al., Plastic Antibodies: Developments and Applications. Trends Biotech. 16: 468-476, 1998.
Hemminki et al., Fine Tuning of an Anti-Testosterone Antibody Binding Site by Stepwise Optimisation of the CDRs. Immunotechnology 4: 59-69, 1998.
Hoogenboom et al, Antibody Phage Display Technology and its Applications. Molecular Immunology 4: 1-20, 1998.
Hoogenboom et al., Natural and Designer Binding Sites Made by Phage Display Technology. Immunology Today 21(8): 371-378, 2000.
Huang et al., The Plasticity of Dendritic Cell Responses to Pathogens and Their Components. Science 294: 870-75, 2001.
Hughes et al., Functional Discovery via a Compendium of Expression Profiles. Cell 102: 109-26, 2000.
Keyomarsi et al., Cyclin E and Survival in Patients with Breast Cancer. N. Eng. J. Med. 347(20):1566-75, 2002.
Li, Applications of Display Technology in Protein Analysis. Nature Biotechnology 18: 1251-1256, 2000.
Li et al., Application of Microfluidic Devices to proteomics Research: Identification of Trace-Level Protein Digests an

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for analyzing proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for analyzing proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for analyzing proteins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2702389

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.